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Glycyrrhetinic Acid

What is it?

Glycyrrhetinic Acid and Glycyrrhizic Acid are specific compounds isolated from licorice plants. Glycyrrhizic Acic is a conjugate of Glycyrhetinic Acid and two molecules of glucuronic acid, a carbohydrate. Potassium Glycyrrhetinate, Sodium Succinoyl Glycyrrhetinate, Glyceryl Glycyrrhetinate, Glycyrrhetinyl Stearate and Stearyl Glycyrrhetinate are salts and esters of Glycyrrhetinic Acid. Ammonium Glycyrrhizate, Dipotassium Glycyrrhizate, Disodium Glycyrrhizate, Trisodium Glycyrrhizate, Methyl Glycyrrhizate and Potassium Glycyrrhizinate are salts and esters of Glycyrrhizic Acid.

In cosmetics and personal care products, these ingredients are used in the formulation of makeup, fragrance, hair care, skin care, shaving, personal hygiene and suntan products.

Safety Information

The Food and Drug Administration (FDA) includes licorice and licorice derivatives on its list of substances considered Generally Recognized As Safe (GRAS) as direct food ingredients with some restrictions on the levels of Glycyrrhizic Acid in certain types of foods. Glycyrrhizic Acid is not permitted as a non-nutritive sweetener in sugar substitutes.

The safety of Glycyrrhetinic Acid, Glycyrrhizic Acid and their salts and esters has been assessed by the Cosmetic Ingredient Review (CIR) Expert Panel. The CIR Expert Panel evaluated the scientific data and concluded that Glycyrrhetinic Acid, Potassium Glycyrrhetinate, Sodium Succinoyl Glycyrrhetinate, Glyceryl Glycyrrhetinate, Glycyrrhetinyl Stearate, Stearyl Glycyrrhetinate, Glycyrrhizic Acid, Ammonium Glycyrrhizate, Dipotassium Glycyrrhizate, Disodium Glycyrrhizate, Trisodium Glycyrrhizate, Methyl Glycyrrhizate and Potassium Glycyrrhizinate were safe for use in cosmetic and personal care products.
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Why is it used in cosmetics and personal care products?

These ingredients are used to enhance the appearance of dry or damaged skin by reducing flaking and restoring suppleness. They are also used to impart a flavor to cosmetics and personal care products.

Scientific facts:

Glycyrrhetinic Acid is an organic compound derived from shredded licorice roots and Glycyrrhizic Acid is a natural material isolated from the licorice plant, Glycyrrhiza glabra.

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